Basic Info

Serotype prediction based on their surface antigens, such as O, H, and K antigens.

More Details

The serotype represents the genetic markers displayed by proteins in blood plasma. Due to the genetic polymorphism of some serum proteins, phenotypic differences arise among individuals. Therefore, serotyping has become an important classification method, especially for many foodborne microorganisms such as Salmonella and Listeria monocytogenes. This method is also widely used in epidemiological investigations. By determining the serotype of bacteria, we can provide a solid basis for antimicrobial therapy. Specifically, through in-depth analysis of the characteristics of bacterial somatic cells, such as the O antigen, cell surface proteins, H antigen, and K antigen, we can accurately classify bacteria based on their serotypes.

What's New

Genes for O-antigen synthesis are normally clustered on the chromosome and named the O-AGC. Genetic variations in O-AGC are the major determinants of differences among the various O-antigens. Based on the genetic variation of O-AGC in M. morganii, 11 distinct O-AGC types were identified. 

Additional Information

NA

Literature

Liu B, Guo X, Wang J, et al. Development of a Molecular Serotyping Scheme for Morganella morganii. Front Microbiol. 2021;12:791165. Published 2021 Nov 23. doi:10.3389/fmicb.2021.791165