Basic Info

Serotype prediction based on their surface antigens, such as O, H, and K antigens.

More Details

The serotype represents the genetic markers displayed by proteins in blood plasma. Due to the genetic polymorphism of some serum proteins, phenotypic differences arise among individuals. Therefore, serotyping has become an important classification method, especially for many foodborne microorganisms such as Salmonella and Listeria monocytogenes. This method is also widely used in epidemiological investigations. By determining the serotype of bacteria, we can provide a solid basis for antimicrobial therapy. Specifically, through in-depth analysis of the characteristics of bacterial somatic cells, such as the O antigen, cell surface proteins, H antigen, and K antigen, we can accurately classify bacteria based on their serotypes.

What's New

The genes involved in surface polysaccharide synthesis are typically arranged in a gene cluster, and the majority of variations among polysaccharides are attributed to genetic variations within the polysaccharide gene clusters (PSgcs). This serves as the molecular basis for serotyping. Currently, E. aerogenes can be classified into 15 serotypes (PSgc1~15) based on PSgc variations.

Additional Information

NA

Literature

Guo X, Wang M, Wang L, et al. Establishment of a Molecular Serotyping Scheme and a Multiplexed Luminex-Based Array for Enterobacter aerogenes. Front Microbiol. 2018;9:501. Published 2018 Mar 19. doi:10.3389/fmicb.2018.00501