Basic Info

Based on the Pathogen-Host Interactions Database (PHI-base), pathogenic genes, virulence genes, effector protein genes, and other relevant genes in pathogens were annotated and predicted.

More Details

PHI-base aggregates experimentally validated or literature-reported pathogenicity genes, virulence genes, and effector protein genes of fungal, oomycete, bacterial, and other pathogen species that can infect plants, animals, fungi, and insects. This database plays a crucial role in research aimed at identifying target genes for drug intervention. Additionally, PHI-base includes antifungal compounds and their corresponding target genes, along with detailed descriptions of the predicted protein functions during the process of host infection.

What's New

NA

Additional Information

Related links:

http://www.phi-base.org/

Literature

Buchfink B, Reuter K, Drost HG. Sensitive protein alignments at tree-of-life scale using DIAMOND. Nat Methods. 2021;18(4):366-368. doi:10.1038/s41592-021-01101-x

Urban M, Cuzick A, Seager J, et al. PHI-base in 2022: a multi-species phenotype database for Pathogen-Host Interactions. Nucleic Acids Res. 2022;50(D1):D837-D847. doi:10.1093/nar/gkab1037