Basic Info

Serotype prediction based on their surface antigens, such as O, H, and K antigens.

More Details

The serotype represents the genetic markers displayed by proteins in blood plasma. Due to the genetic polymorphism of some serum proteins, phenotypic differences arise among individuals. Therefore, serotyping has become an important classification method, especially for many foodborne microorganisms such as Salmonella and Listeria monocytogenes. This method is also widely used in epidemiological investigations. By determining the serotype of bacteria, we can provide a solid basis for antimicrobial therapy. Specifically, through in-depth analysis of the characteristics of bacterial somatic cells, such as the O antigen, cell surface proteins, H antigen, and K antigen, we can accurately classify bacteria based on their serotypes.

What's New

The capsular polysaccharide is the basis for the typing system of Streptococcus Suis (S. suis). S. suis had originally been classified into 35 serotypes (1/2 and 1–34) based on the antigenicity of the capsular polysaccharide, which is suggested to be a major virulent factor. Because some described serotypes (serotypes 20, 22, 26, 32, 33, and 34) belong to other bacterial species, the number of official S. suis serotypes has been reduced to 29. However, after 2010, serotypes 21/29, NCL21-NCL26 (novel cps loci), and Chz were described in China.

Additional Information

NA

Literature

Nicholson TL, Kalalah AA, Eppinger M. Population structure and genetic diversity of Streptococcus suis isolates obtained from the United States. Front Microbiol. 2023;14:1250265. Published 2023 Sep 21. doi:10.3389/fmicb.2023.1250265

Obradovic MR, Segura M, Segalés J, Gottschalk M. Review of the speculative role of co-infections in Streptococcus suis-associated diseases in pigs. Vet Res. 2021;52(1):49. Published 2021 Mar 20. doi:10.1186/s13567-021-00918-w

Wang X, Sun J, Bian C, et al. The population structure, antimicrobial resistance, and pathogenicity of Streptococcus suis cps31. Vet Microbiol. 2021;259:109149. doi:10.1016/j.vetmic.2021.109149

Liu Z, Zheng H, Gottschalk M, et al. Development of multiplex PCR assays for the identification of the 33 serotypes of Streptococcus suis. PLoS One. 2013;8(8):e72070. Published 2013 Aug 9. doi:10.1371/journal.pone.0072070