Genomic islands (GIs) are clusters of genes in prokaryotic genomes of probable horizontal origin. GIs are disproportionately associated with microbial adaptations of medical or environmental interest.They can be predicted based on differences in genomic sequence composition among bacteria of different species. Alternatively, whole-genome sequence alignment can be used to identify large DNA fragments that are present in a specific genome but absent in the genomes of closely related bacterial strains.
IslandPath-DIMOB is a standalone software to predict genomic islands in bacterial and archaeal genomes based on the presence of dinucleotide biases and mobility genes.
Related links:
https://github.com/brinkmanlab/islandpath
Bertelli C, Brinkman FSL. Improved genomic island predictions with IslandPath-DIMOB. Bioinformatics. 2018;34(13):2161-2167. doi:10.1093/bioinformatics/bty095